منابع مشابه
Lipid Peroxide Formation in Microsomes
or ferricyanide were not able to replace ascorbate and induce lipid peroxide formation. 2. The rate of ascorbate-induced peroxidation is optimum at pH 6-0 whereas the rate of the NADPH system is optimum at pH7-0. Both systems require phosphate for maximum activity. 3. Lipid peroxide formation occurs at the maximum specific rate in very dilute microsome suspensions (0-15mg. of protein/ ml.). 4. ...
متن کاملLipid metabolism by gut microbes and atherosclerosis.
A recent metabolomic study provides evidence that microbial metabolism of lipids in the gut yields product(s) that promote atherosclerosis. These results add another dimension—the microbiome—to the complex determinants of atherogenesis. Atherosclerotic vascular disease is a complex pathophenotype that is governed by genetic and environmental determinants. The mechanistic interplay between speci...
متن کاملSuperoxide dismutase activity, lipid peroxide production
was explored during various stages of pseudopregnancy, including natural and induced luteal regression. Induced luteolysis was achieved during mid-pseudopregnancy by removal of an oestradiol capsule placed at the onset of pseudopregnancy, which suppressed ovarian oestradiol production. Activity of manganese superoxide dismutase (Mn SOD) was significantly and positively correlated with ovarian p...
متن کاملMicroRNAs in lipid metabolism and atherosclerosis.
Numerous studies have examined the role of microRNAs (miRNAs) in cell homeostasis and cardiovascular disease and have markedly improved our understanding of RNA biology in general and the potential role of miRNAs in atherosclerosis. In atherosclerosis, several miRNAs, such as miR-33a,b, miR-92a, miR-126 and others, have been identified that are relevant mediators of pathological processes, incl...
متن کاملApolipoprotein E and atherosclerosis: beyond lipid effect.
In humans, apolipoprotein E (apoE) is a polymorphic multifunctional protein.1 It is coded by three alleles ( 2, 3, 4) of a modulator gene (level, variability, and susceptibility gene) at the apoE locus on chromosome 19, determining six apoE genotypes and plasma phenotypes. Its pleiotropic effects are exerted on plasma lipoprotein metabolism, coagulation, oxidative processes, macrophage, glial c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1986
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.13.6_1509